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Bone marrow adipocytes promote the Warburg phenotype in metastatic prostate tumors via HIF-1α activation

Metabolic adaptation is increasingly recognized as a key factor in tumor progression, yet its involvement in metastatic bone disease is not understood. Bone is as an adipocyte-rich organ, and a major site of metastasis from prostate cancer. Bone marrow adipocytes are metabolically active cells capab...

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Detalles Bibliográficos
Autores principales:	Diedrich, Jonathan D., Rajagurubandara, Erandi, Herroon, Mackenzie K., Mahapatra, Gargi, Hüttemann, Maik, Podgorski, Izabela
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Impact Journals LLC 2016
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5323121/ https://www.ncbi.nlm.nih.gov/pubmed/27588494 http://dx.doi.org/10.18632/oncotarget.11712

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