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Immunohistochemical correlates of TP53 somatic mutations in cancer

Despite controversy on the correlation between p53 accumulation and TP53 mutational status, ihas long been used as a surrogate method for mutation analysis. The aim of our study was to characterise the IHC expression features of TP53 somatic mutations and define their occurrence in human cancers. A...

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Detalles Bibliográficos
Autores principales: Murnyák, Balázs, Hortobágyi, Tibor
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5323125/
https://www.ncbi.nlm.nih.gov/pubmed/27626311
http://dx.doi.org/10.18632/oncotarget.11912