Synthetic ligands of death receptor 5 display a cell-selective agonistic effect at different oligomerization levels

DR4 (Death Receptor 4) and DR5 (Death Receptor 5) are two potential targets for cancer therapy due to their ability to trigger apoptosis of cancer cells, but not normal ones, when activated by their cognate ligand TRAIL (TNF related apoptosis-inducing ligand). Therapies based on soluble recombinant...

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Detalles Bibliográficos
Autores principales: Beyrath, Julien, Chekkat, Neila, Smulski, Cristian R., Lombardo, Caterina M., Lechner, Marie-Charlotte, Seguin, Cendrine, Decossas, Marion, Spanedda, Maria Vittoria, Frisch, Benoît, Guichard, Gilles, Fournel, Sylvie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5323128/
https://www.ncbi.nlm.nih.gov/pubmed/27409341
http://dx.doi.org/10.18632/oncotarget.10508

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5323128/
https://www.ncbi.nlm.nih.gov/pubmed/27409341
http://dx.doi.org/10.18632/oncotarget.10508

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