Proto-oncogenic miR-744 is upregulated by transcription factor c-Jun via a promoter activation mechanism

Upregulation of miR-744 is associated with poor prognosis in many types of cancer patients, but it is still unclear how miR-744 becomes elevated in these tumors. In this study, we found that ectopic c-Jun elevated miR-744 expression, whereas c-Jun attenuation reduced miR-744 expression. Chromatin im...

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Detalles Bibliográficos
Autores principales: Sha, Zhou, Zhu, Xiaoxia, Li, Na, Li, Yiyi, Li, Dianhe
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5323131/
https://www.ncbi.nlm.nih.gov/pubmed/27533465
http://dx.doi.org/10.18632/oncotarget.11285

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5323131/
https://www.ncbi.nlm.nih.gov/pubmed/27533465
http://dx.doi.org/10.18632/oncotarget.11285

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