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Proto-oncogenic miR-744 is upregulated by transcription factor c-Jun via a promoter activation mechanism
Upregulation of miR-744 is associated with poor prognosis in many types of cancer patients, but it is still unclear how miR-744 becomes elevated in these tumors. In this study, we found that ectopic c-Jun elevated miR-744 expression, whereas c-Jun attenuation reduced miR-744 expression. Chromatin im...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Impact Journals LLC
2016
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5323131/ https://www.ncbi.nlm.nih.gov/pubmed/27533465 http://dx.doi.org/10.18632/oncotarget.11285 |