RALB provides critical survival signals downstream of Ras in acute myeloid leukemia

Mutations that activate RAS proto-oncogenes and their effectors are common in acute myeloid leukemia (AML); however, efforts to therapeutically target Ras or its effectors have been unsuccessful, and have been hampered by an incomplete understanding of which effectors are required for AML proliferat...

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Detalles Bibliográficos
Autores principales: Eckfeldt, Craig E., Pomeroy, Emily J., Lee, Robin D.W., Hazen, Katherine S., Lee, Lindsey A., Moriarity, Branden S., Largaespada, David A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5323144/
https://www.ncbi.nlm.nih.gov/pubmed/27556501
http://dx.doi.org/10.18632/oncotarget.11431

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5323144/
https://www.ncbi.nlm.nih.gov/pubmed/27556501
http://dx.doi.org/10.18632/oncotarget.11431

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