SIRT1-mediated FoxOs pathways protect against apoptosis by promoting autophagy in osteoblast-like MC3T3-E1 cells exposed to sodium fluoride

Fluorine may result in damage to teeth, bones and other body tissues, and is a serious public health problem. SIRT1 deacetylates FOXOs, which brings about apoptosis and autophagy promotion or suppression. Fluorine may induce cell apoptosis, however, the role of autophagy in apoptosis induced by fluo...

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Detalles Bibliográficos
Autores principales: Gu, Xiaolong, Han, Dandan, Chen, Wei, Zhang, Limei, Lin, Qianyun, Gao, Jian, Fanning, Séamus, Han, Bo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5323150/
https://www.ncbi.nlm.nih.gov/pubmed/27564107
http://dx.doi.org/10.18632/oncotarget.11573

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5323150/
https://www.ncbi.nlm.nih.gov/pubmed/27564107
http://dx.doi.org/10.18632/oncotarget.11573

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