Foxp3 enhances HIF-1α target gene expression in human bladder cancer through decreasing its ubiquitin-proteasomal degradation

Hypoxia-inducible factor-1α (HIF-1α) can control a transcriptional factor forkhead box P3 (Foxp3) protein expression in T lymphocyte differentiation through proteasome-mediated degradation. In this study, we unveil a reverse regulatory mechanism contributing to bladder cancer progression; Foxp3 expr...

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Detalles Bibliográficos
Autores principales: Jou, Yeong-Chin, Tsai, Yuh-Shyan, Lin, Chang-Te, Tung, Chun-Liang, Shen, Cheng-Huang, Tsai, Hsin-Tzu, Yang, Wen-Horng, Chang, Hung-I, Chen, Syue-Yi, Tzai, Tzong-Shin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5323164/
https://www.ncbi.nlm.nih.gov/pubmed/27557492
http://dx.doi.org/10.18632/oncotarget.11395

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5323164/
https://www.ncbi.nlm.nih.gov/pubmed/27557492
http://dx.doi.org/10.18632/oncotarget.11395

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