TGFβ upregulates PAR-1 expression and signalling responses in A549 lung adenocarcinoma cells

The major high-affinity thrombin receptor, proteinase activated receptor-1 (PAR-1) is expressed at low levels by the normal epithelium but is upregulated in many types of cancer, including lung cancer. The thrombin-PAR-1 signalling axis contributes to the activation of latent TGFβ in response to tis...

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Detalles Bibliográficos
Autores principales: Smoktunowicz, Natalia, Platé, Manuela, Stern, Alejandro Ortiz, D'Antongiovanni, Vanessa, Robinson, Eifion, Chudasama, Vijay, Caddick, Stephen, Scotton, Chris J., Jarai, Gabor, Chambers, Rachel C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5323169/
https://www.ncbi.nlm.nih.gov/pubmed/27566553
http://dx.doi.org/10.18632/oncotarget.11472

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5323169/
https://www.ncbi.nlm.nih.gov/pubmed/27566553
http://dx.doi.org/10.18632/oncotarget.11472

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