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TGFβ upregulates PAR-1 expression and signalling responses in A549 lung adenocarcinoma cells

The major high-affinity thrombin receptor, proteinase activated receptor-1 (PAR-1) is expressed at low levels by the normal epithelium but is upregulated in many types of cancer, including lung cancer. The thrombin-PAR-1 signalling axis contributes to the activation of latent TGFβ in response to tis...

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Detalles Bibliográficos
Autores principales:	Smoktunowicz, Natalia, Platé, Manuela, Stern, Alejandro Ortiz, D'Antongiovanni, Vanessa, Robinson, Eifion, Chudasama, Vijay, Caddick, Stephen, Scotton, Chris J., Jarai, Gabor, Chambers, Rachel C.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Impact Journals LLC 2016
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5323169/ https://www.ncbi.nlm.nih.gov/pubmed/27566553 http://dx.doi.org/10.18632/oncotarget.11472

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