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Paradoxical overexpression of MBNL2 in hepatocellular carcinoma inhibits tumor growth and invasion

Pre-mRNA alternative splicing is an essential step in the process of gene expression. It provides cells with the opportunity to create various protein isoforms. Disruptions of alternative splicing are associated with various diseases, including cancer. The muscleblind-like (MBNL) protein is a splici...

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Detalles Bibliográficos
Autores principales: Lee, Yu-Hsin, Jhuang, Yu-Lin, Chen, Yu-Ling, Jeng, Yung-Ming, Yuan, Ray-Hwang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5323177/
https://www.ncbi.nlm.nih.gov/pubmed/27564110
http://dx.doi.org/10.18632/oncotarget.11577