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Glutathione may have implications in the design of 3-bromopyruvate treatment protocols for both fungal and algal infections as well as multiple myeloma

In different fungal and algal species, the intracellular concentration of reduced glutathione (GSH) correlates closely with their susceptibility to killing by the small molecule alkylating agent 3-bromopyruvate (3BP). Additionally, in the case of Cryptococcus neoformans cells 3BP exhibits a synergis...

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Detalles Bibliográficos
Autores principales: Niedźwiecka, Katarzyna, Dyląg, Mariusz, Augustyniak, Daria, Majkowska-Skrobek, Grażyna, Cal-Bąkowska, Magdalena, Ko, Young H., Pedersen, Peter L., Goffeau, Andre, Ułaszewski, Stanisław
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5323179/
https://www.ncbi.nlm.nih.gov/pubmed/27582536
http://dx.doi.org/10.18632/oncotarget.11592