Activation of autophagic flux by epigallocatechin gallate mitigates TRAIL-induced tumor cell apoptosis via down-regulation of death receptors

Epigallocatechin gallate (EGCG) is a major polyphenol in green tea. Recent studies have reported that EGCG can inhibit TRAIL-induced apoptosis and activate autophagic flux in cancer cells. However, the mechanism behind these processes is unclear. The present study found that EGCG prevents tumor cell...

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Detalles Bibliográficos
Autores principales: Kim, Sung-Wook, Moon, Ji-Hong, Park, Sang-Youel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5323182/
https://www.ncbi.nlm.nih.gov/pubmed/27582540
http://dx.doi.org/10.18632/oncotarget.11597

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5323182/
https://www.ncbi.nlm.nih.gov/pubmed/27582540
http://dx.doi.org/10.18632/oncotarget.11597

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