Eupafolin enhances TRAIL-mediated apoptosis through cathepsin S-induced down-regulation of Mcl-1 expression and AMPK-mediated Bim up-regulation in renal carcinoma Caki cells

Eupafolin, a flavone found in Artemisia princeps, has been reported for its anti-tumor activity in several cancer cells. In this study, we examined whether eupafolin could sensitize TRAIL-mediated apoptosis in human renal carcinoma Caki cells. We found that eupafolin alone and TRAIL alone had no eff...

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Detalles Bibliográficos
Autores principales: Han, Min Ae, Min, Kyoung-jin, Woo, Seon Min, Seo, Bo Ram, Kwon, Taeg Kyu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5323186/
https://www.ncbi.nlm.nih.gov/pubmed/27582546
http://dx.doi.org/10.18632/oncotarget.11604

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5323186/
https://www.ncbi.nlm.nih.gov/pubmed/27582546
http://dx.doi.org/10.18632/oncotarget.11604

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