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Eupafolin enhances TRAIL-mediated apoptosis through cathepsin S-induced down-regulation of Mcl-1 expression and AMPK-mediated Bim up-regulation in renal carcinoma Caki cells
Eupafolin, a flavone found in Artemisia princeps, has been reported for its anti-tumor activity in several cancer cells. In this study, we examined whether eupafolin could sensitize TRAIL-mediated apoptosis in human renal carcinoma Caki cells. We found that eupafolin alone and TRAIL alone had no eff...
Autores principales: | Han, Min Ae, Min, Kyoung-jin, Woo, Seon Min, Seo, Bo Ram, Kwon, Taeg Kyu |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5323186/ https://www.ncbi.nlm.nih.gov/pubmed/27582546 http://dx.doi.org/10.18632/oncotarget.11604 |
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