LY6E: a conductor of malignant tumor growth through modulation of the PTEN/PI3K/Akt/HIF-1 axis

Lymphocyte antigen 6 complex, locus E (LY6E) has been implicated in the malignant progression of various types of cancers; however, the underlying mechanism remains unclear. Here, we identified LY6E as an activator of HIF-1 and revealed their mechanistic and functional links in malignant tumor growt...

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Detalles Bibliográficos
Autores principales: Yeom, Chan Joo, Zeng, Lihua, Goto, Yoko, Morinibu, Akiyo, Zhu, Yuxi, Shinomiya, Kazumi, Kobayashi, Minoru, Itasaka, Satoshi, Yoshimura, Michio, Hur, Cheol-Goo, Kakeya, Hideaki, Hammond, Ester M., Hiraoka, Masahiro, Harada, Hiroshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5323196/
https://www.ncbi.nlm.nih.gov/pubmed/27589564
http://dx.doi.org/10.18632/oncotarget.11670

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5323196/
https://www.ncbi.nlm.nih.gov/pubmed/27589564
http://dx.doi.org/10.18632/oncotarget.11670

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