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LY6E: a conductor of malignant tumor growth through modulation of the PTEN/PI3K/Akt/HIF-1 axis
Lymphocyte antigen 6 complex, locus E (LY6E) has been implicated in the malignant progression of various types of cancers; however, the underlying mechanism remains unclear. Here, we identified LY6E as an activator of HIF-1 and revealed their mechanistic and functional links in malignant tumor growt...
Autores principales: | Yeom, Chan Joo, Zeng, Lihua, Goto, Yoko, Morinibu, Akiyo, Zhu, Yuxi, Shinomiya, Kazumi, Kobayashi, Minoru, Itasaka, Satoshi, Yoshimura, Michio, Hur, Cheol-Goo, Kakeya, Hideaki, Hammond, Ester M., Hiraoka, Masahiro, Harada, Hiroshi |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5323196/ https://www.ncbi.nlm.nih.gov/pubmed/27589564 http://dx.doi.org/10.18632/oncotarget.11670 |
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