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UBE2C is overexpressed in ESCC tissues and its abrogation attenuates the malignant phenotype of ESCC cell lines

The esophageal squamous cell carcinoma (ESCC) is widely known as a highly lethal and poor understood cancer, then requiring the search for novel molecular markers to improve its management and patients survival. Recently, ubiquitin-conjugating enzyme E2C (UBE2C) has been figuring as a prominent tumo...

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Detalles Bibliográficos
Autores principales: Palumbo, Antonio, Costa, Nathalia Meireles Da, De Martino, Marco, Sepe, Romina, Pellecchia, Simona, Leite de Sousa, Vanessa Paiva, Neto, Pedro Nicolau, Kruel, Cleber Dario, Bergman, Anke, Nasciutti, Luiz Eurico, Fusco, Alfredo, Pinto, Luis Felipe Ribeiro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5323199/
https://www.ncbi.nlm.nih.gov/pubmed/27588470
http://dx.doi.org/10.18632/oncotarget.11674