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Cancer stem cells from human glioblastoma resemble but do not mimic original tumors after in vitro passaging in serum-free media

Human gliomas harbour cancer stem cells (CSCs) that evolve along the course of the disease, forming highly heterogeneous subpopulations within the tumour mass. These cells possess self-renewal properties and appear to contribute to tumour initiation, metastasis and resistance to therapy. CSC culture...

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Detalles Bibliográficos
Autores principales: García-Romero, Noemí, González-Tejedo, Carmen, Carrión-Navarro, Josefa, Esteban-Rubio, Susana, Rackov, Gorjana, Rodríguez-Fanjul, Vanessa, Cruz, Jorge Oliver-De La, Prat-Acín, Ricardo, Peris-Celda, María, Blesa, David, Ramírez-Jiménez, Laura, Sánchez-Gómez, Pilar, Perona, Rosario, Escobedo-Lucea, Carmen, Belda-Iniesta, Cristobal, Ayuso-Sacido, Angel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5323200/
https://www.ncbi.nlm.nih.gov/pubmed/27589567
http://dx.doi.org/10.18632/oncotarget.11676