Cargando…

Inhibition of never in mitosis A (NIMA)-related kinase-4 reduces survivin expression and sensitizes cancer cells to TRAIL-induced cell death

The tumor necrosis factor-related apoptosis inducing ligand (TRAIL) preferentially induces apoptosis in cancer cells. However, many tumors are resistant to TRAIL-induced apoptosis, and resistance mechanisms are not fully understood. To identify novel regulatory molecules of TRAIL resistance, we scre...

Descripción completa

Detalles Bibliográficos
Autores principales: Park, So Jung, Jo, Doo Sin, Jo, Se-Young, Shin, Dong Woon, Shim, Sangmi, Jo, Yoon Kyung, Shin, Ji Hyun, Ha, Ye Jin, Jeong, Seong-Yun, Hwang, Jung Jin, Kim, Young Sam, Suh, Young-Ah, Chang, Jong Wook, Kim, Jin Cheon, Cho, Dong-Hyung
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5323206/
https://www.ncbi.nlm.nih.gov/pubmed/27602754
http://dx.doi.org/10.18632/oncotarget.11781