Pancreatic stellate cell secreted IL-6 stimulates STAT3 dependent invasiveness of pancreatic intraepithelial neoplasia and cancer cells

Pancreatic ductal adenocarcinoma (PDAC) is a dynamic tumor supported by several stromal elements such as pancreatic stellate cells (PSC). Significant crosstalk exists between PSCs and tumor cells to stimulate oncogenic signaling and malignant progression of PDAC. However, how PSCs activate intercell...

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Detalles Bibliográficos
Autores principales: Nagathihalli, Nagaraj S., Castellanos, Jason A., VanSaun, Michael N., Dai, Xizi, Ambrose, Mahogany, Guo, Qiaozhi, Xiong, Yanhua, Merchant, Nipun B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5323208/
https://www.ncbi.nlm.nih.gov/pubmed/27602757
http://dx.doi.org/10.18632/oncotarget.11786

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5323208/
https://www.ncbi.nlm.nih.gov/pubmed/27602757
http://dx.doi.org/10.18632/oncotarget.11786

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