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Sialylation transmogrifies human breast and pancreatic cancer cells into 3D multicellular tumor spheroids using cyclic RGD-peptide induced self-assembly

Multicellular tumor spheroids (MTS) have been at the forefront of cancer research, designed to mimic tumor-like developmental patterns in vitro. Tumor growth in vivo is highly influenced by aberrant cell surface-specific sialoglycan structures on glycoproteins. Aberrant sialoglycan patterns that fac...

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Detalles Bibliográficos
Autores principales: Akasov, Roman, Haq, Sabah, Haxho, Fiona, Samuel, Vanessa, Burov, Sergey V., Markvicheva, Elena, Neufeld, Ronald J., Szewczuk, Myron R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5323220/
https://www.ncbi.nlm.nih.gov/pubmed/27608845
http://dx.doi.org/10.18632/oncotarget.11868