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Patient-derived xenograft models of colorectal cancer in pre-clinical research: a systematic review
AIMS: We sought to objectively assess the internal and external validity of patient-derived xenograft (PDX) models as a platform in pre-clinical research into colorectal cancer (CRC). Metastatic disease is the most common cause of death from CRC, and despite significant research, the results of curr...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5323228/ https://www.ncbi.nlm.nih.gov/pubmed/27517155 http://dx.doi.org/10.18632/oncotarget.11184 |