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Patient-derived xenograft models of colorectal cancer in pre-clinical research: a systematic review

AIMS: We sought to objectively assess the internal and external validity of patient-derived xenograft (PDX) models as a platform in pre-clinical research into colorectal cancer (CRC). Metastatic disease is the most common cause of death from CRC, and despite significant research, the results of curr...

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Detalles Bibliográficos
Autores principales:	Brown, Kai M., Xue, Aiqun, Mittal, Anubhav, Samra, Jaswinder S., Smith, Ross, Hugh, Thomas J.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Impact Journals LLC 2016
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5323228/ https://www.ncbi.nlm.nih.gov/pubmed/27517155 http://dx.doi.org/10.18632/oncotarget.11184

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