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m(6)A-dependent maternal mRNA clearance facilitates zebrafish maternal-to-zygotic transition

The maternal-to-zygotic transition (MZT) is one of the most profound and orchestrated processes during the early life of embryos, yet factors that shape the temporal pattern of vertebrate MZT are largely unknown. Here we show that over one-third of zebrafish maternal messenger RNAs (mRNAs) can be N(...

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Detalles Bibliográficos
Autores principales: Zhao, Boxuan Simen, Wang, Xiao, Beadell, Alana V., Lu, Zhike, Shi, Hailing, Kuuspalu, Adam, Ho, Robert K., He, Chuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5323276/
https://www.ncbi.nlm.nih.gov/pubmed/28192787
http://dx.doi.org/10.1038/nature21355