Cellular Pathology of Pelizaeus-Merzbacher Disease Involving Chaperones Associated with Endoplasmic Reticulum Stress

Disease-causing mutations in genes encoding membrane proteins may lead to the production of aberrant polypeptides that accumulate in the endoplasmic reticulum (ER). These mutant proteins have detrimental conformational changes or misfolding events, which result in the triggering of the unfolded prot...

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Detalles Bibliográficos
Autor principal: Inoue, Ken
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2017
Materias:
Molecular Biosciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5323380/
https://www.ncbi.nlm.nih.gov/pubmed/28286750
http://dx.doi.org/10.3389/fmolb.2017.00007

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5323380/
https://www.ncbi.nlm.nih.gov/pubmed/28286750
http://dx.doi.org/10.3389/fmolb.2017.00007

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