Computational Identification of Amino-Acid Mutations that Further Improve the Activity of a Chalcone–Flavonone Isomerase from Glycine max

Protein design for improving enzymatic activity remains a challenge in biochemistry, especially to identify target amino-acid sites for mutagenesis and to design beneficial mutations for those sites. Here, we employ a computational approach that combines multiple sequence alignment, positive selecti...

Descripción completa

Detalles Bibliográficos
Autores principales: Yuan, Hui, Wu, Jiaqi, Wang, Xiaoqiang, Chen, Jiakuan, Zhong, Yang, Huang, Qiang, Nan, Peng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2017
Materias:
Plant Science
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5323383/
https://www.ncbi.nlm.nih.gov/pubmed/28286513
http://dx.doi.org/10.3389/fpls.2017.00248

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5323383/
https://www.ncbi.nlm.nih.gov/pubmed/28286513
http://dx.doi.org/10.3389/fpls.2017.00248

Ejemplares similares