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Diet-Induced Obesity Does Not Alter Tigecycline Treatment Efficacy in Murine Lyme Disease

Obese individuals more frequently suffer from infections, as a result of increased susceptibility to a number of bacterial pathogens. Furthermore, obesity can alter antibiotic treatment efficacy due to changes in drug pharmacokinetics which can result in under-dosing. However, studies on the treatme...

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Detalles Bibliográficos
Autores principales: Pětrošová, Helena, Eshghi, Azad, Anjum, Zoha, Zlotnikov, Nataliya, Cameron, Caroline E., Moriarty, Tara J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5323460/
https://www.ncbi.nlm.nih.gov/pubmed/28286500
http://dx.doi.org/10.3389/fmicb.2017.00292