Reduction of dopamine D(2/3) receptor binding in the striatum after a single administration of esketamine, but not R-ketamine: a PET study in conscious monkeys

R-ketamine appears to be a potent, long-lasting and safer antidepressant, relative to esketamine (S-ketamine), since it might be free of psychotomimetic side effects. Using [(11)C]raclopride and positron emission tomography (PET), we investigated whether esketamine and R-ketamine can affect dopamine...

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Detalles Bibliográficos
Autores principales: Hashimoto, Kenji, Kakiuchi, Takeharu, Ohba, Hiroyuki, Nishiyama, Shingo, Tsukada, Hideo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2016
Materias:
Short Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5323469/
https://www.ncbi.nlm.nih.gov/pubmed/27091456
http://dx.doi.org/10.1007/s00406-016-0692-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5323469/
https://www.ncbi.nlm.nih.gov/pubmed/27091456
http://dx.doi.org/10.1007/s00406-016-0692-7

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