Synthesis and pre-clinical evaluation of a new class of high-affinity (18)F-labeled PSMA ligands for detection of prostate cancer by PET imaging

PURPOSE: Current clinical imaging of PSMA-positive prostate cancer by positron emission tomography (PET) mainly features (68)Ga-labeled tracers, notably [(68)Ga]Ga-PSMA-HBED-CC. The longer half-life of fluorine-18 offers significant advantages over Ga-68, clinically and logistically. We aimed to dev...

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Detalles Bibliográficos
Autores principales: Kelly, James, Amor-Coarasa, Alejandro, Nikolopoulou, Anastasia, Kim, Dohyun, Williams, Clarence, Ponnala, Shashikanth, Babich, John W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2016
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5323493/
https://www.ncbi.nlm.nih.gov/pubmed/27847991
http://dx.doi.org/10.1007/s00259-016-3556-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5323493/
https://www.ncbi.nlm.nih.gov/pubmed/27847991
http://dx.doi.org/10.1007/s00259-016-3556-5

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