Functional and cardioprotective effects of simultaneous and individual activation of protein kinase A and Epac

BACKGROUND AND PURPOSE: Myocardial cAMP elevation confers cardioprotection against ischaemia/reperfusion (I/R) injury. cAMP activates two independent signalling pathways, PKA and Epac. This study investigated the cardiac effects of activating PKA and/or Epac and their involvement in cardioprotection...

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Detalles Bibliográficos
Autores principales: Khaliulin, Igor, Bond, Mark, James, Andrew F, Dyar, Zara, Amini, Raheleh, Johnson, Jason L, Suleiman, M‐Saadeh
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2017
Materias:
Research Papers
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5323515/
https://www.ncbi.nlm.nih.gov/pubmed/28071786
http://dx.doi.org/10.1111/bph.13709

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5323515/
https://www.ncbi.nlm.nih.gov/pubmed/28071786
http://dx.doi.org/10.1111/bph.13709

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