Autophagy activated by tuberin/mTOR/p70S6K suppression is a protective mechanism against local anaesthetics neurotoxicity

The local anaesthetics (LAs) are widely used for peripheral nerve blocks, epidural anaesthesia, spinal anaesthesia and pain management. However, exposure to LAs for long duration or at high dosage can provoke potential neuronal damages. Autophagy is an intracellular bulk degradation process for prot...

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Detalles Bibliográficos
Autores principales: Xiong, Jingwei, Kong, Qiuyue, Dai, Leyang, Ma, He, Cao, Xiaofei, Liu, Li, Ding, Zhengnian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2016
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5323818/
https://www.ncbi.nlm.nih.gov/pubmed/27860187
http://dx.doi.org/10.1111/jcmm.13003

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5323818/
https://www.ncbi.nlm.nih.gov/pubmed/27860187
http://dx.doi.org/10.1111/jcmm.13003

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