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Macrophages of genetically characterized familial hypercholesterolaemia patients show up‐regulation of LDL‐receptor‐related proteins

Familial hypercholesterolaemia (FH) is a major risk for premature coronary heart disease due to severe long‐life exposure to high LDL levels. Accumulation of LDL in the vascular wall triggers atherosclerosis with activation of the innate immunity system. Here, we have investigated (i) gene expressio...

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Detalles Bibliográficos
Autores principales: Escate, Rafael, Padro, Teresa, Borrell‐Pages, Maria, Suades, Rosa, Aledo, Rosa, Mata, Pedro, Badimon, Lina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5323824/
https://www.ncbi.nlm.nih.gov/pubmed/27680891
http://dx.doi.org/10.1111/jcmm.12993