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Macrophages of genetically characterized familial hypercholesterolaemia patients show up‐regulation of LDL‐receptor‐related proteins
Familial hypercholesterolaemia (FH) is a major risk for premature coronary heart disease due to severe long‐life exposure to high LDL levels. Accumulation of LDL in the vascular wall triggers atherosclerosis with activation of the innate immunity system. Here, we have investigated (i) gene expressio...
Autores principales: | Escate, Rafael, Padro, Teresa, Borrell‐Pages, Maria, Suades, Rosa, Aledo, Rosa, Mata, Pedro, Badimon, Lina |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5323824/ https://www.ncbi.nlm.nih.gov/pubmed/27680891 http://dx.doi.org/10.1111/jcmm.12993 |
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