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MicroRNA‐21 protects against cardiac hypoxia/reoxygenation injury by inhibiting excessive autophagy in H9c2 cells via the Akt/mTOR pathway

MicroRNAs and autophagy play critical roles in cardiac hypoxia/reoxygenation (H/R)‐induced injury. Here, we investigated the function of miR‐21 in regulating autophagy and identified the potential molecular mechanisms involved. To determine the role of miR‐21 in regulating autophagy, H9c2 cells were...

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Detalles Bibliográficos
Autores principales: Huang, Zhouqing, Wu, Shengjie, Kong, Fanqi, Cai, Xueli, Ye, Bozhi, Shan, Peiren, Huang, Weijian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5323864/
https://www.ncbi.nlm.nih.gov/pubmed/27680680
http://dx.doi.org/10.1111/jcmm.12990