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FAK contributes to proteinuria in hypercholesterolaemic rats and modulates podocyte F‐actin re‐organization via activating p38 in response to ox‐LDL

Focal adhesion kinase (FAK) is a non‐receptor protein tyrosine kinase that regulates cell adhesion, proliferation and differentiation. In the present study, a rat model of high fat diet‐induced hypercholesterolaemia was established to investigate the involvement of FAK in lipid disorder‐related kidn...

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Detalles Bibliográficos
Autores principales: Hu, Mengsi, Fan, Minghua, Zhen, Junhui, Lin, Jiangong, Wang, Qun, Lv, Zhimei, Wang, Rong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5323874/
https://www.ncbi.nlm.nih.gov/pubmed/27704688
http://dx.doi.org/10.1111/jcmm.13001