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The anti‐ageing hormone klotho induces Nrf2‐mediated antioxidant defences in human aortic smooth muscle cells

Vascular ageing in conditions such as atherosclerosis, diabetes and chronic kidney disease, is associated with the activation of the renin angiotensin system (RAS) and diminished expression of antioxidant defences mediated by the transcription factor nuclear factor erythroid 2‐related factor 2 (Nrf2...

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Detalles Bibliográficos
Autores principales: Maltese, Giuseppe, Psefteli, Paraskevi‐Maria, Rizzo, Benedetta, Srivastava, Salil, Gnudi, Luigi, Mann, Giovanni E., Siow, Richard C.M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5323877/
https://www.ncbi.nlm.nih.gov/pubmed/27696667
http://dx.doi.org/10.1111/jcmm.12996