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Naringin in Ganshuang Granule suppresses activation of hepatic stellate cells for anti‐fibrosis effect by inhibition of mammalian target of rapamycin

A previous study has demonstrated that Ganshuang granule (GSG) plays an anti‐fibrotic role partially by deactivation of hepatic stellate cells (HSCs). In HSCs activation, mammalian target of rapamycin (mTOR)‐autophagy plays an important role. We attempted to investigate the role of mTOR‐autophagy in...

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Detalles Bibliográficos
Autores principales: Shi, Hongbo, Shi, Honglin, Ren, Feng, Chen, Dexi, Chen, Yu, Duan, Zhongping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5323881/
https://www.ncbi.nlm.nih.gov/pubmed/27687505
http://dx.doi.org/10.1111/jcmm.12994