Attenuated secretion of glucose-dependent insulinotropic polypeptide (GIP) does not alleviate hyperphagic obesity and insulin resistance in ob/ob mice

OBJECTIVE: Glucose-dependent insulinotropic polypeptide (GIP) is released during meals and promotes nutrient uptake and storage. GIP receptor knockout mice are protected from diet induced weight gain and thus GIP antagonists have been proposed as a treatment for obesity. In this study, we assessed t...

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Detalles Bibliográficos
Autores principales: Shimazu-Kuwahara, Satoko, Harada, Norio, Yamane, Shunsuke, Joo, Erina, Sankoda, Akiko, Kieffer, Timothy J., Inagaki, Nobuya
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2017
Materias:
Brief Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5324019/
https://www.ncbi.nlm.nih.gov/pubmed/28271035
http://dx.doi.org/10.1016/j.molmet.2017.01.006

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5324019/
https://www.ncbi.nlm.nih.gov/pubmed/28271035
http://dx.doi.org/10.1016/j.molmet.2017.01.006

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