Bromodomain and Extra-Terminal Protein Inhibition Attenuates Neutrophil-dominant Allergic Airway Disease

Atopic asthma is a prevalent respiratory disease that is characterized by inflammation, mucus hypersecretion, and airway hyperresponsiveness. The complexity of this heterogeneous disorder has commanded the need to better define asthma phenotypes based on underlying molecular mechanisms of disease. A...

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Detalles Bibliográficos
Autores principales: Manni, Michelle L., Mandalapu, Sivanarayana, Salmeron, Andres, Lora, Jose M., Kolls, Jay K., Alcorn, John F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5324049/
https://www.ncbi.nlm.nih.gov/pubmed/28233801
http://dx.doi.org/10.1038/srep43139

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5324049/
https://www.ncbi.nlm.nih.gov/pubmed/28233801
http://dx.doi.org/10.1038/srep43139

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