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Bromodomain and Extra-Terminal Protein Inhibition Attenuates Neutrophil-dominant Allergic Airway Disease
Atopic asthma is a prevalent respiratory disease that is characterized by inflammation, mucus hypersecretion, and airway hyperresponsiveness. The complexity of this heterogeneous disorder has commanded the need to better define asthma phenotypes based on underlying molecular mechanisms of disease. A...
Autores principales: | Manni, Michelle L., Mandalapu, Sivanarayana, Salmeron, Andres, Lora, Jose M., Kolls, Jay K., Alcorn, John F. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5324049/ https://www.ncbi.nlm.nih.gov/pubmed/28233801 http://dx.doi.org/10.1038/srep43139 |
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