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Mechanical diagnosis of human erythrocytes by ultra-high speed manipulation unraveled critical time window for global cytoskeletal remodeling

Large deformability of erythrocytes in microvasculature is a prerequisite to realize smooth circulation. We develop a novel tool for the three-step “Catch-Load-Launch” manipulation of a human erythrocyte based on an ultra-high speed position control by a microfluidic “robotic pump”. Quantification o...

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Detalles Bibliográficos
Autores principales: Ito, Hiroaki, Murakami, Ryo, Sakuma, Shinya, Tsai, Chia-Hung Dylan, Gutsmann, Thomas, Brandenburg, Klaus, Pöschl, Johannes M. B., Arai, Fumihito, Kaneko, Makoto, Tanaka, Motomu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5324053/
https://www.ncbi.nlm.nih.gov/pubmed/28233788
http://dx.doi.org/10.1038/srep43134