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Long-term homeostasis and wound healing in an in vitro epithelial stem cell niche model

Cultures of epithelial cells are limited by the proliferative capacity of primary cells and cell senescence. Herein we show that primary human epithelial cell sheets cultured without dermal equivalents maintained homeostasis in vitro for at least 1 year. Transparency of these sheets enabled live obs...

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Detalles Bibliográficos
Autores principales: Miyashita, Hideyuki, Niwano, Hiroko, Yoshida, Satoru, Hatou, Shin, Inagaki, Emi, Tsubota, Kazuo, Shimmura, Shigeto
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5324070/
https://www.ncbi.nlm.nih.gov/pubmed/28233843
http://dx.doi.org/10.1038/srep43557