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Long-term homeostasis and wound healing in an in vitro epithelial stem cell niche model
Cultures of epithelial cells are limited by the proliferative capacity of primary cells and cell senescence. Herein we show that primary human epithelial cell sheets cultured without dermal equivalents maintained homeostasis in vitro for at least 1 year. Transparency of these sheets enabled live obs...
Autores principales: | Miyashita, Hideyuki, Niwano, Hiroko, Yoshida, Satoru, Hatou, Shin, Inagaki, Emi, Tsubota, Kazuo, Shimmura, Shigeto |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5324070/ https://www.ncbi.nlm.nih.gov/pubmed/28233843 http://dx.doi.org/10.1038/srep43557 |
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