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The chaperone-like activity of the hepatitis C virus IRES and CRE elements regulates genome dimerization

The RNA genome of the hepatitis C virus (HCV) establishes a network of long-distance RNA-RNA interactions that direct the progression of the infective cycle. This work shows that the dimerization of the viral genome, which is initiated at the dimer linkage sequence (DLS) within the 3′UTR, is promote...

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Detalles Bibliográficos
Autores principales: Romero-López, Cristina, Barroso-delJesus, Alicia, Berzal-Herranz, Alfredo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5324077/
https://www.ncbi.nlm.nih.gov/pubmed/28233845
http://dx.doi.org/10.1038/srep43415