Cargando…
The chaperone-like activity of the hepatitis C virus IRES and CRE elements regulates genome dimerization
The RNA genome of the hepatitis C virus (HCV) establishes a network of long-distance RNA-RNA interactions that direct the progression of the infective cycle. This work shows that the dimerization of the viral genome, which is initiated at the dimer linkage sequence (DLS) within the 3′UTR, is promote...
Autores principales: | Romero-López, Cristina, Barroso-delJesus, Alicia, Berzal-Herranz, Alfredo |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2017
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5324077/ https://www.ncbi.nlm.nih.gov/pubmed/28233845 http://dx.doi.org/10.1038/srep43415 |
Ejemplares similares
-
The folding of the hepatitis C virus internal ribosome entry site depends on the 3′-end of the viral genome
por: Romero-López, Cristina, et al.
Publicado: (2012) -
End-to-end crosstalk within the hepatitis C virus genome mediates the conformational switch of the 3′X-tail region
por: Romero-López, Cristina, et al.
Publicado: (2014) -
RNA Aptamers as Molecular Tools to Study the Functionality of the Hepatitis C Virus CRE Region
por: Fernández-Sanlés, Alba, et al.
Publicado: (2015) -
The cis-acting replication element of the Hepatitis C virus genome recruits host factors that influence viral replication and translation
por: Ríos-Marco, Pablo, et al.
Publicado: (2016) -
The Role of the RNA-RNA Interactome in the Hepatitis C Virus Life Cycle
por: Romero-López, Cristina, et al.
Publicado: (2020)