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Sample size determination for a binary response in a superiority clinical trial using a hybrid classical and Bayesian procedure
BACKGROUND: When designing studies that have a binary outcome as the primary endpoint, the hypothesized proportion of patients in each population experiencing the endpoint of interest (i.e., π (1),π (2)) plays an important role in sample size and power calculations. Point estimates for π (1) and π (...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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BioMed Central
2017
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5324236/ https://www.ncbi.nlm.nih.gov/pubmed/28231813 http://dx.doi.org/10.1186/s13063-017-1791-0 |