Spatiotemporal progression of ubiquitin-proteasome system inhibition after status epilepticus suggests protective adaptation against hippocampal injury

BACKGROUND: The ubiquitin-proteasome-system (UPS) is the major intracellular pathway leading to the degradation of unwanted and/or misfolded soluble proteins. This includes proteins regulating cellular survival, synaptic plasticity and neurotransmitter signaling; processes controlling excitability t...

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Detalles Bibliográficos
Autores principales: Engel, Tobias, Martinez-Villarreal, Jaime, Henke, Christine, Jimenez-Mateos, Eva M., Sanz-Rodriguez, Amaya, Alves, Mariana, Hernandez-Santana, Yasmina, Brennan, Gary P., Kenny, Aidan, Campbell, Aoife, Lucas, Jose J., Henshall, David C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5324261/
https://www.ncbi.nlm.nih.gov/pubmed/28235423
http://dx.doi.org/10.1186/s13024-017-0163-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5324261/
https://www.ncbi.nlm.nih.gov/pubmed/28235423
http://dx.doi.org/10.1186/s13024-017-0163-2

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