Cargando…

Spatiotemporal progression of ubiquitin-proteasome system inhibition after status epilepticus suggests protective adaptation against hippocampal injury

BACKGROUND: The ubiquitin-proteasome-system (UPS) is the major intracellular pathway leading to the degradation of unwanted and/or misfolded soluble proteins. This includes proteins regulating cellular survival, synaptic plasticity and neurotransmitter signaling; processes controlling excitability t...

Descripción completa

Detalles Bibliográficos
Autores principales:	Engel, Tobias, Martinez-Villarreal, Jaime, Henke, Christine, Jimenez-Mateos, Eva M., Sanz-Rodriguez, Amaya, Alves, Mariana, Hernandez-Santana, Yasmina, Brennan, Gary P., Kenny, Aidan, Campbell, Aoife, Lucas, Jose J., Henshall, David C.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2017
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5324261/ https://www.ncbi.nlm.nih.gov/pubmed/28235423 http://dx.doi.org/10.1186/s13024-017-0163-2

Ejemplares similares

Altered Biogenesis and MicroRNA Content of Hippocampal Exosomes Following Experimental Status Epilepticus
por: Batool, Aasia, et al.
Publicado: (2020)

Deletion of the BH3-only protein Noxa alters electrographic seizures but does not protect against hippocampal damage after status epilepticus in mice
por: Ichikawa, Naoki, et al.
Publicado: (2017)

Bi-directional genetic modulation of GSK-3β exacerbates hippocampal neuropathology in experimental status epilepticus
por: Engel, Tobias, et al.
Publicado: (2018)

P2X7 Receptor-Dependent microRNA Expression Profile in the Brain Following Status Epilepticus in Mice
por: Conte, Giorgia, et al.
Publicado: (2020)

Transgenic Overexpression of 14-3-3 Zeta Protects Hippocampus against Endoplasmic Reticulum Stress and Status Epilepticus In Vivo
por: Brennan, Gary P., et al.
Publicado: (2013)

Targeting the proteasome in epilepsy
por: Engel, Tobias, et al.
Publicado: (2017)

Genetic deletion of microRNA-22 blunts the inflammatory transcriptional response to status epilepticus and exacerbates epilepsy in mice
por: Almeida Silva, Luiz F., et al.
Publicado: (2020)

P2X receptors as targets for the treatment of status epilepticus
por: Henshall, David C., et al.
Publicado: (2013)

Loss of p53 results in protracted electrographic seizures and development of an aggravated epileptic phenotype following status epilepticus
por: Engel, T, et al.
Publicado: (2010)

MicroRNAs in the pathophysiology and treatment of status epilepticus
por: Henshall, David C.
Publicado: (2013)

Spatiotemporal profile of Map2 and microglial changes in the hippocampal CA1 region following pilocarpine-induced status epilepticus
por: Schartz, Nicole D., et al.
Publicado: (2016)

The ubiquitin-proteasome pathway in cancer.
por: Spataro, V., et al.
Publicado: (1998)

The ubiquitin proteasome system in neuropathology
por: Lehman, Norman L.
Publicado: (2009)

The recognition of ubiquitinated proteins by the proteasome
por: Grice, Guinevere L., et al.
Publicado: (2016)

MicroRNA-22 Controls Aberrant Neurogenesis and Changes in Neuronal Morphology After Status Epilepticus
por: Beamer, Edward H., et al.
Publicado: (2018)

The Ubiquitin Conjugating Enzyme: An Important Ubiquitin Transfer Platform in Ubiquitin-Proteasome System
por: Liu, Weigang, et al.
Publicado: (2020)

Poxvirus Exploitation of the Ubiquitin-Proteasome System
por: Barry, Michele, et al.
Publicado: (2010)

The Ubiquitin-Proteasome Pathway in Huntington's Disease
por: Mitra, Siddhartha, et al.
Publicado: (2008)

Enzymatic Blockade of the Ubiquitin-Proteasome Pathway
por: Ernst, Robert, et al.
Publicado: (2011)

The ubiquitin-proteasome system in Alzheimer's disease
por: Oddo, Salvatore
Publicado: (2008)

Autoregulation of the 26S proteasome by in situ ubiquitination
por: Jacobson, Andrew D., et al.
Publicado: (2014)

Ubiquitin Proteasome System in Stress and Disease
por: Karpov, Dmitry, et al.
Publicado: (2012)

Intracellular Dynamics of the Ubiquitin-Proteasome-System
por: Chowdhury, Maisha, et al.
Publicado: (2015)

Ubiquitin-Proteasome System in Neurodegenerative Disorders
por: Rao, Geeta, et al.
Publicado: (2015)

The Ubiquitin–Proteasome System in Immune Cells
por: Çetin, Gonca, et al.
Publicado: (2021)

Ubiquitin-proteasome system in diabetic retinopathy
por: Svikle, Zane, et al.
Publicado: (2022)

Copper homeostasis and the ubiquitin proteasome system
por: Zhang, Bichao, et al.
Publicado: (2023)

The Ubiquitin–Proteasome System in Tumor Metabolism
por: Wang, Jie, et al.
Publicado: (2023)

Hippocampal glucocorticoid receptors modulate status epilepticus severity
por: Kraus, Kimberly L., et al.
Publicado: (2023)

The Ubiquitin Proteasome System Plays a Role in Venezuelan Equine Encephalitis Virus Infection
por: Amaya, Moushimi, et al.
Publicado: (2015)

Delineation of molecular pathway activities of the chronic antidepressant treatment response suggests important roles for glutamatergic and ubiquitin–proteasome systems
por: Park, D I, et al.
Publicado: (2017)

The role of the ubiquitination-proteasome pathway in breast cancer: Applying drugs that affect the ubiquitin-proteasome pathway to the therapy of breast cancer
por: Orlowski, Robert Z, et al.
Publicado: (2003)

Polypharmacology of small molecules targeting the ubiquitin–proteasome and ubiquitin-like systems
por: Amelio, Ivano, et al.
Publicado: (2015)

Interplay between the Ubiquitin Proteasome System and Ubiquitin-Mediated Autophagy in Plants
por: Su, Tong, et al.
Publicado: (2020)

Ubiquitin-like protein conjugation and the ubiquitin–proteasome system as drug targets
por: Bedford, Lynn, et al.
Publicado: (2010)

Ubiquitin Engineering for Interrogating the Ubiquitin–Proteasome System and Novel Therapeutic Strategies
por: Tang, Jason Q., et al.
Publicado: (2023)

RU486 Mitigates Hippocampal Pathology Following Status Epilepticus
por: Wulsin, Aynara C., et al.
Publicado: (2016)

Mitochondrial transplantation ameliorates hippocampal damage following status epilepticus
por: Jia, Xiaoxia, et al.
Publicado: (2023)

The ubiquitin–proteasome system in spongiform degenerative disorders
por: Whatley, Brandi R., et al.
Publicado: (2008)

Role of the ubiquitin proteasome system in Alzheimer's disease
por: Upadhya, Sudarshan C, et al.
Publicado: (2007)

Cannot write session to /tmp/vufind_sessions/sess_tfg5h6m441rm3vl8jc3tonmlq3