Network topology of NaV1.7 mutations in sodium channel-related painful disorders

BACKGROUND: Gain-of-function mutations in SCN9A gene that encodes the voltage-gated sodium channel NaV1.7 have been associated with a wide spectrum of painful syndromes in humans including inherited erythromelalgia, paroxysmal extreme pain disorder and small fibre neuropathy. These mutations change...

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Detalles Bibliográficos
Autores principales: Kapetis, Dimos, Sassone, Jenny, Yang, Yang, Galbardi, Barbara, Xenakis, Markos N., Westra, Ronald L., Szklarczyk, Radek, Lindsey, Patrick, Faber, Catharina G., Gerrits, Monique, Merkies, Ingemar S. J., Dib-Hajj, Sulayman D., Mantegazza, Massimo, Waxman, Stephen G., Lauria, Giuseppe
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5324268/
https://www.ncbi.nlm.nih.gov/pubmed/28235406
http://dx.doi.org/10.1186/s12918-016-0382-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5324268/
https://www.ncbi.nlm.nih.gov/pubmed/28235406
http://dx.doi.org/10.1186/s12918-016-0382-0

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